Individualized rate of absorption
The key to the safety and tolerability of Ferralet® 90 is the biocomplementary manner in which it is solubilized and absorbed.* As gastric acid interacts with the carbonyl iron, it is solubilized for absorption.1 Balance is maintained between the production of soluble iron and its uptake by the intestines. Despite this more gradual absorption, however, the increases in mucosal ferritin, total absorption, and internal distribution are equivalent between carbonyl iron and ferrous sulfate.
Excellent tolerability and safety
This remarkable iron results in no significant difference in GI side effects even when dosed at 10 times the standard dose of ferrous sulfate.2 And it's far less toxic when ingested by children. In Conn's Current Therapy 2008, carbonyl iron is cited as "the oral therapy of choice for most persons, because it causes less gastrointestinal toxicity than iron salts and is equally effective in correcting iron deficiency."3
Designed to make iron therapy more pleasant for patients
Ferralet 90 addresses traditional drawbacks of iron therapy. The gentle stool softener docusate sodium eases constipation in iron-sensitive women. The vanilla scent improves the taste and smell normally associated with iron therapy. And, with a formulation free of lactose and gluten, many dietary concerns are met.
* Data based on animal studies.
- Huebers HA, Brittenham GM, Csiba E, Finch CA. Absorption of carbonyl iron. J Lab Clin Med. 1986 Nov;108(5):473-8.
- Brittenham GM, Klein HG, Kushner JP, Ajioka RS. Preserving the national blood supply. Hematology Am Soc Hematol Educ Program. 2001;:422-32.
- Barton JC. Iron deficiency. In Rakel RE, Bope ET. Conn's Current Therapy, 2008. Amsterdam, The Netherlands: Saunders/Elsevier, 385-389.